The Saudi Dental Journal
Volume 22, Issue 3 , Pages 129-131 , July 2010

Levels of gingival crevicular metalloproteinases-8 and -9 in periodontitis

Received 14 June 2008 ,Revised 9 April 2009 ,Accepted 9 December 2009.

References 

  1. Alpagot T, Bell C, Lundergan W, Chambers DW, Rudin R. Longitudinal evaluation of GCF MMP-3 and TIMP-1 levels as prognostic factors for progression of periodontitis. J. Clin. Periodontol. 2001;28:353–359
  2. Caton JG, Ciancio SG, Blieden TM, Bradshaw M, Crout RJ, Hefti AF, et al. Subantimicrobial dose doxycycline as an adjunct to scaling and root planing: post-treatment effects. J. Clin. Periodontol. 2001;8:782–789
  3. Cazalis J, Tanabe S, Gagnon G, Sorsa T, Grenier D. Tetracyclines and chemically modified tetracycline-3 (CMT-3) modulate cytokine secretion by lipopolysaccharide-stimulated whole blood. Inflammation. 2009;32(2):130–137
  4. Chang YC, Yang SF, Lai CC, Liu JY, Hsieh YS. Regulation of matrix metalloproteinase production by cytokines, pharmacological agents and periodontal pathogens in human periodontal ligament fibroblast cultures. J. Periodontal Res. 2000;37:196–203
  5. Cota LOM, Guimarães AN, Costa JE, Lorentz TCM, Costa FO. Association between maternal periodontitis and an increased risk of preeclampsia. J Periodontol. 2006;77:2063–2069
  6. Delaissé JM, Engsig MT, Everts V, del Carmen Ovejero M, Ferreras M, Lund L, et al. Proteinases in bone resorption: obvious and less obvious roles. Clin. Chim. Acta. 2000;291:223–224
  7. Gangbar S, Overall CM, McCulloch CA, Sodek J. Identification of polymorphonuclear leukocyte collagenase and gelatinase activities in mouthrinse samples: correlation with periodontal disease activity in adult and juvenile periodontitis. J. Periodontal Res. 1990;25:257–267
  8. Hutter G, Schlagenhauf U, Valenza G, Horn M, Burgemeister S, Claus H, et al. Molecular analysis of bacteria in periodontitis: evaluation of clone libraries, novel phylotypes and putative pathogens. Microbiology. 2003;149:67–75
  9. Ingman T, Sorsa T, Michaelis J, Konttinen YT. Matrix metalloproteinases-1, -3, and -8 in adult periodontitis in situ. An immunohistochemical study. Ann. NY Acad. Sci. 1994;732:459–461
  10. Kinane DF. Causation and pathogenesis of periodontal disease. Periodontol. 2001;25:8–20
  11. Korostoff JM, Wang JF, Sarment DP, Stewart JC, Feldman RS, Billings PC. Analysis of in situ protease activity in chronic adult periodontitis patients: expression of activated MMP-2 and a 40kDa serine protease. J. Periodontol. 2000;1:353–360
  12. Maeso G, Bravo M, Bascones A. Levels of metalloproteinase-2 and -9 and tissue inhibitor of matrix metalloproteinase-1 in gingival crevicular fluid of patients with periodontitis, gingivitis, and healthy gingiva. Quintessence Int. 2007;38:247–252
  13. Mäkelä M, Salo T, Uitto VJ, Larjava H. Matrix metalloproteinases (MMP-2 and MMP-9) of the oral cavity: cellular origin and relationship to periodontal status. J. Dent. Res. 1994;73:1397–1406
  14. Miller CS, King CP, Langub MC, Kryscio RJ, Thomas MV. Salivary biomarkers of existing periodontal disease: a cross-sectional study. J. Am. Dent. Assoc. 2006;137:322–329
  15. Navazesh M. Methods for collecting saliva. Ann. NY Acad. Sci. 2003;694:72–77
  16. Novak MJ, Johns LP, Miller RC, Bradshaw MH. Adjunctive benefits of subantimicrobial dose doxycycline in the management of severe, generalized, chronic periodontitis. J. Periodontol. 2002;73:762–769
  17. Passoja A, Ylipalosaari M, Tervonen T, Raunio T, Knuuttila M. Matrix metalloproteinase-8 concentration in shallow crevices associated with the extent of periodontal disease. J. Clin. Periodontol. 2008;35(12):1027–1031
  18. Rai B, Kharb S, Anand SC. Thiocynate, a salivary marker of periodontitis among smokers and nonsmokers: a pilot study. J. Pak. Dent. Assoc. 2007;16:35–37
  19. Sorsa T, Suomalainen K, Uitto VJ. The role of gingival crevicular fluid and salivary interstitial collagenases in human periodontal diseases. Arch. Oral Biol. 1990;35(Suppl.):193S–196S
  20. Villela B, Cogen RB, Bartolucci AA, Birkedal-Hansen H. Collagenolytic activity in crevicular fluid from patients with chronic adult periodontitis, localized juvenile periodontitis and gingivitis, and from healthy control subjects. J. Periodontal Res. 1987;22:381–389
  21. Woessner JF. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J. 1994;5:2145–2154

PII: S1013-9052(10)00044-1

doi: 10.1016/j.sdentj.2010.04.006

The Saudi Dental Journal
Volume 22, Issue 3 , Pages 129-131 , July 2010

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